Cholinesterases and Anticholinesterase Agents

Cholinesterases and Anticholinesterase Agents
Author :
Publisher : Springer Science & Business Media
Total Pages : 1228
Release :
ISBN-10 : 9783642998751
ISBN-13 : 3642998755
Rating : 4/5 (755 Downloads)

Book Synopsis Cholinesterases and Anticholinesterase Agents by : George B. Koelle

Download or read book Cholinesterases and Anticholinesterase Agents written by George B. Koelle and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 1228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although the anticholinesterase (anti-ChE) agents have only limited applica tions in therapy, and from the viewpoint of practical significance they are more appropriately classified as toxic compounds or insecticides than as drugs, in their capacity of pharmacological tools they have few equals. The concept of neuro humoral transmission was originally established largely from experiments in which physostigmine, or eserine, was employed to protect acetylcholine (ACh), the trans mitter of the cholinergic nerves, from rapid hydrolytic destruction by acetyl cholinesterase (AChE) and other cholinesterases (ChE's). Since then, a great num ber of additional reversible and irreversible anti-ChE agents also have been indis pensable in studies of synaptic and neuroeffector transmission, and of other physiological processes. At the same time, there is practically no other class of compounds for which a mechanism of pharmacological action can be described in such concrete biochemical and physiological terms. Consequently, it is not sur prising that a huge literature has developed on these several closely interdependent topics. The assembling anrl proper correlation of this material for the present volume has taken the collaborative efforts of over two dozen . investigators. It iR believed that their contributions to this end will prove invaluable to future in vestigators in providing a ready, inclusive source of established information, in defining areas where further studies are indicated, and in preventing unnecessary duplication of past work. How well these aims have been accomplished will be for time and the reader to judge.


Cholinesterases and Anticholinesterase Agents Related Books

Cholinesterases and Anticholinesterase Agents
Language: en
Pages: 1228
Authors: George B. Koelle
Categories: Medical
Type: BOOK - Published: 2013-11-11 - Publisher: Springer Science & Business Media

DOWNLOAD EBOOK

Although the anticholinesterase (anti-ChE) agents have only limited applica tions in therapy, and from the viewpoint of practical significance they are more app
Cholinesterases and Cholinesterase Inhibitors
Language: en
Pages: 280
Authors: Ezio Giacobini
Categories: Science
Type: BOOK - Published: 2000-04-03 - Publisher: CRC Press

DOWNLOAD EBOOK

With the collaboration of the most distinguished scholars in this field Professor Giacobini has put together a publication which will convey present knowledge i
Enzymes of the Cholinesterase Family
Language: en
Pages: 524
Authors: A.S. Balasubramanian
Categories: Science
Type: BOOK - Published: 2013-11-11 - Publisher: Springer Science & Business Media

DOWNLOAD EBOOK

The Fifth International Meeting on Cholinesterases convened in Madras, India, in September of 1994. The long and rich history and culture of India provided an e
The Protest Psychosis
Language: en
Pages: 319
Authors: Jonathan M. Metzl
Categories: Psychology
Type: BOOK - Published: 2010-01-01 - Publisher: Beacon Press

DOWNLOAD EBOOK

A powerful account of how cultural anxieties about race shaped American notions of mental illness The civil rights era is largely remembered as a time of sit-in
The Biology of Cholinesterases
Language: en
Pages: 620
Authors: Ann Silver
Categories: Medical
Type: BOOK - Published: 1974 - Publisher: North-Holland

DOWNLOAD EBOOK