Exploring Novel Clinical Trial Designs for Gene-Based Therapies

Exploring Novel Clinical Trial Designs for Gene-Based Therapies
Author :
Publisher : National Academies Press
Total Pages : 127
Release :
ISBN-10 : 9780309672986
ISBN-13 : 0309672988
Rating : 4/5 (988 Downloads)

Book Synopsis Exploring Novel Clinical Trial Designs for Gene-Based Therapies by : National Academies of Sciences, Engineering, and Medicine

Download or read book Exploring Novel Clinical Trial Designs for Gene-Based Therapies written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-08-27 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognizing the potential design complexities and ethical issues associated with clinical trials for gene therapies, the Forum on Regenerative Medicine of the National Academies of Sciences, Engineering, and Medicine held a 1-day workshop in Washington, DC, on November 13, 2019. Speakers at the workshop discussed patient recruitment and selection for gene-based clinical trials, explored how the safety of new therapies is assessed, reviewed the challenges involving dose escalation, and spoke about ethical issues such as informed consent and the role of clinicians in recommending trials as options to their patients. The workshop also included discussions of topics related to gene therapies in the context of other available and potentially curative treatments, such as bone marrow transplantation for hemoglobinopathies. This publication summarizes the presentation and discussion of the workshop.


Exploring Novel Clinical Trial Designs for Gene-Based Therapies Related Books

Exploring Novel Clinical Trial Designs for Gene-Based Therapies
Language: en
Pages: 127
Authors: National Academies of Sciences, Engineering, and Medicine
Categories: Medical
Type: BOOK - Published: 2020-08-27 - Publisher: National Academies Press

DOWNLOAD EBOOK

Recognizing the potential design complexities and ethical issues associated with clinical trials for gene therapies, the Forum on Regenerative Medicine of the N
Gene Therapy - From Laboratory To The Clinic
Language: en
Pages: 289
Authors: Kam M Hui
Categories: Science
Type: BOOK - Published: 1994-11-29 - Publisher: World Scientific

DOWNLOAD EBOOK

With advances in our understanding of the molecular biology of human diseases and the development of efficient gene transfer techniques, the treatment of such d
Cellular Transplantation
Language: en
Pages: 699
Authors: Craig Halberstadt
Categories: Science
Type: BOOK - Published: 2011-10-10 - Publisher: Elsevier

DOWNLOAD EBOOK

There have been tremendous strides in cellular transplantation in recent years, leading to accepted practice for the treatment of certain diseases, and use for
Gene Therapy Technologies, Applications and Regulations
Language: en
Pages: 450
Authors: Anthony Meager
Categories: Medical
Type: BOOK - Published: 1999 - Publisher: John Wiley & Sons

DOWNLOAD EBOOK

This text brings together the current data previously separated. It combines information on gene therapy technologies and the attendant regulatory requirements
Translating Regenerative Medicine to the Clinic
Language: en
Pages: 356
Authors: Jeffrey Laurence
Categories: Technology & Engineering
Type: BOOK - Published: 2015-11-18 - Publisher: Academic Press

DOWNLOAD EBOOK

Translating Regenerative Medicine to the Clinic reviews the current methodological tools and experimental approaches used by leading translational researchers,