Download or read book Binding Partners Regulate Eyes Absent-Sine Oculis Transcriptional Output During Retinal Development in Drosophila Melanogaster written by Trevor Lewis Davis and published by . This book was released on 2017 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each cell in a developing organism undergoes a defined sequence of developmental events to reach its final functional state. At decision points along their path to terminal differentiation, cells interpret a subset of the available instructions encoded by the genome to select the correct developmental trajectory. Molecularly, combinations of transcription factors initiate and stabilize these cellular decisions by activating context-specific gene expression program. Thus, understanding how transcription factors are regulated to generate diverse developmental outcomes is a fundamental challenge in biology.