Principles of Process Research and Chemical Development in the Pharmaceutical Industry
Author | : Oljan Repic |
Publisher | : Wiley-Interscience |
Total Pages | : 248 |
Release | : 1998 |
ISBN-10 | : UOM:39015042161185 |
ISBN-13 | : |
Rating | : 4/5 ( Downloads) |
Download or read book Principles of Process Research and Chemical Development in the Pharmaceutical Industry written by Oljan Repic and published by Wiley-Interscience. This book was released on 1998 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text discusses the functions of Process R&D (research and development), which involves the method of transforming a research synthetic procedure into a plant process and the key aspects of a synthesis that must be considered when scaling up a process. Topics consist of: basic principles of chemical development; techniques for the minimization of by-product impurities; criteria for cost-effective synthesis of enantiopure compounds by resolutions; asymmetric synthesis, and "chiral pool" strategy; synthesis for labeling substances with hydrogen or carbon isotopes; and last, licensing.