The Synthesis of Sterically Demanding Ligands and Examples of Their Copper Complexes
Author | : Ryan D. Rieth |
Publisher | : |
Total Pages | : 104 |
Release | : 2004 |
ISBN-10 | : OCLC:59133289 |
ISBN-13 | : |
Rating | : 4/5 ( Downloads) |
Download or read book The Synthesis of Sterically Demanding Ligands and Examples of Their Copper Complexes written by Ryan D. Rieth and published by . This book was released on 2004 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conditions for promoting the Pd-catalyzed arylation of (N-pyrrolyl)zinc derivatives have been established using aryl bromides, chlorides, and iodides as substrates. In most cases, 0.5 mol% Pd(OAc)2 can achieve the desired transformation in roughly 24 hours, with the more sterically demanding substrates requiring altered conditions. Typical isolated yields are in excess of 70%. Moreover, methyl- and aryl-substituted pyrrolyl anions have been shown to display similar chemistry using 5.0 mol% Pd(OAc)2. Though they require longer reaction times, the isolated yields rival those of the unsubstituted analogs. Two new copper(I) N-heterocyclic carbene complexes containing the 2,4,6,2",4",6"--Hexaisopropyl-1,1':3',1"-terphenyl moiety have been synthesized and isolated. The LCuCl complex (92% isolated yield) was made via a one-pot synthesis from the corresponding imidazolinium tetrafluoroborate salt, NaH, and CuCl (L = [1,3-bis-(2,4,6,2",4",6"-hexaisopropyl- [1,1':3',1"]terphenyl-5'-yl)-4,5-dihydroimidazol-2-ylidene]). The LCuOAc complex (71% isolated yield) was made the same way using CuOAc in place of CuCl.