Download or read book 23 European Symposium on Computer Aided Process Engineering written by Weifeng Chen and published by Elsevier Inc. Chapters. This book was released on 2013-06-10 with total page 17 pages. Available in PDF, EPUB and Kindle. Book excerpt: Real-time optimization (RTO) has become a standard practice to improve production benefits during the past years. The efficiency of solving optimization problems is critical because a large computational delay leads to the possible loss of validity and availability of RTO. In this study, the Mnemonic Enhancement Optimization (MEO) strategy of initialization for RTO has been extended by taking advantage of optimal sensitivity. The approximation precision and the solution information database accumulation efficiency of the proposed sensitivity-based MEO are briefly analyzed. The numerical results tested with a high-pressure column of a cryogenic air separation unit were in agreement with the theoretical analysis.