Binding Partners Regulate Eyes Absent-Sine Oculis Transcriptional Output During Retinal Development in Drosophila Melanogaster
Author | : Trevor Lewis Davis |
Publisher | : |
Total Pages | : 259 |
Release | : 2017 |
ISBN-10 | : 0355079305 |
ISBN-13 | : 9780355079302 |
Rating | : 4/5 (302 Downloads) |
Download or read book Binding Partners Regulate Eyes Absent-Sine Oculis Transcriptional Output During Retinal Development in Drosophila Melanogaster written by Trevor Lewis Davis and published by . This book was released on 2017 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each cell in a developing organism undergoes a defined sequence of developmental events to reach its final functional state. At decision points along their path to terminal differentiation, cells interpret a subset of the available instructions encoded by the genome to select the correct developmental trajectory. Molecularly, combinations of transcription factors initiate and stabilize these cellular decisions by activating context-specific gene expression program. Thus, understanding how transcription factors are regulated to generate diverse developmental outcomes is a fundamental challenge in biology.