Download or read book Biomedical Applications of Microprobe Analysis (APS Colloquium, 2005). written by and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Microprobe analysis in biology is used here mainly in the context of acquisition and analysis of compositional data at cellular and subcellular spatial resolutions using microbeams on the nanometer scale. Clearly this is only one aspect of a very broad field of scientific inquiry that generally falls under the rubric of compositional imaging that can involve many different sources of radiation including electrons, ions, and photons. Indeed there are often subtle distinctions in biological microscopy between structural microanatomy and chemical microanatomy - they obviously can be significantly different, for example during the early stages of cell injury when changes in the elemental distribution within a cell can become readily apparent before any observable changes in morphology via conventional microscopy. [See the entire abstract at http://www.aps.anl.gov/News/Meetings/APS_Colloquium/2005/IngramAbstr_long1.pdf].