Download or read book Signal Transduction in Mast Cells and Basophils written by Ehud Razin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focussing on the molecular mechanisms that govern mast cell and basophil cell biology and function, this book also provides a comprehensive summary of the field of signal transduction, giving insights into areas that have therapeutic potential. It gives detailed insights into mast cell and basophil growth and development, their activation by allergens, including details of receptor activation and downstream events, and the regulators of morphology and degranulation. The metabolic pathways involved in prostaglandin and leukotriene production are discussed as is the role of transcription factors in mast cell growth and cytokine production. Written by leaders in the field, this volume will provide readers with an up-to-date account of a topic whose rapid progress makes conventional information gathering difficult.