Download or read book Synthesis of Polystyrene (PS)-polyhedral Oligomeric Silsesquioxane (POSS)-based Giant Molecules with Sequence-controlled POSS Heads written by Siyu Zhang and published by . This book was released on 2016 with total page 35 pages. Available in PDF, EPUB and Kindle. Book excerpt: The design and the synthesis of sequence-controlled linear giant molecules by controlling the sequences and functionalities precisely are great challenges in the field of macromolecular chemistry. In this article, we designed a method to synthesize sequence-controlled linear giant molecules by using two different kinds of polyhedral oligomeric silsesquioxanes (POSSes) based building blocks. Five POSSes heads were attached successively and alternately as a linear chain with a polystyrene tail as a purification tag via azide-alkyne cycloaddition (SPAAC) "click" reactions, oxime ligations, and thiol-ene "click" coupling (TECC). In order to precisely test controlled sequences and functionalities of the POSSes heads, we used many different characterizations, 1HNMR spectra, 13CNMR spectra, FT-IR spectra, UV-vis spectra, and GPC traces, to characterize every precursor of the giant molecules. 1HNMR and 13CNMR also showed the change of the vinyl groups on VPOSSes after TECC reactions. This study pioneers the synthesis for giant molecules with accurately controlled sequences, functionalities, compositions, and topologies. Furthermore, these features defined giant molecules can also be used to test several specific supermolecular self-assembling behaviors.